Linker Information
General Information of This Linker
| Linker ID |
LIN0OVBRO
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| Linker Name |
Cleavable ester linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C71H119N17O31
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| Isosmiles |
[H][C@@]12CCc3[nH]nnc3CC[C@]1([H])[C@@H]2COC(=O)NCCOCCOCCNC(=O)CCC(=O)NCC(=O)NCCOCCC(=O)NCCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](COC(=O)NCCC(=O)N[C@@H](CCC(=O)N[C@@H](C)C(=O)O)C(=O)O)C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOC
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| InChI |
InChI=1S/C71H119N17O31/c1-48(68(101)102)83-60(93)8-7-54(69(103)104)84-61(94)12-15-76-70(105)119-47-55(67(100)75-18-23-110-29-30-113-33-34-115-37-38-117-40-39-116-36-35-114-32-31-112-26-25-107-2)85-66(99)45-82-65(98)44-81-64(97)43-80-63(96)42-79-58(91)11-14-72-59(92)13-20-108-21-17-74-62(95)41-78-57(90)10-9-56(89)73-16-22-109-27-28-111-24-19-77-71(106)118-46-51-49-3-5-52-53(87-88-86-52)6-4-50(49)51/h48-51,54-55H,3-47H2,1-2H3,(H,72,92)(H,73,89)(H,74,95)(H,75,100)(H,76,105)(H,77,106)(H,78,90)(H,79,91)(H,80,96)(H,81,97)(H,82,98)(H,83,93)(H,84,94)(H,85,99)(H,101,102)(H,103,104)(H,86,87,88)/t48-,49-,50+,51-,54-,55-/m0/s1
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| InChIKey |
NOGWFLAKIOHPHB-ZRWVUPPZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1706.821
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Polar area
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643.56
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Complexity
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1705.82579
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xlogp Value
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-7.7695
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Heavy Count
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119
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Rot Bonds
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71
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Hbond acc
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31
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Hbond Donor
|
17
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Each Antibody-drug Conjugate Related to This Linker