Linker Information
General Information of This Linker
| Linker ID |
LIN0OTQPT
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| Linker Name |
CN108853514B-Cet-4S-2M-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C48H75N9O19
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| Isosmiles |
OCC1=CC=C(NC(/C(NC(COCC(NCCOCCOOCCOOCCOOCCOOCCOOCCOCCN2C=C(CNCC3CCC(CN4C(C=CC4=O)=O)CC3)N=N2)=O)=O)=C\CCCN)=O)C=C1
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| InChI |
InChI=1S/C48H75N9O19/c49-14-2-1-3-43(48(63)52-41-10-8-40(35-58)9-11-41)53-45(60)37-66-36-44(59)51-15-17-64-19-21-67-69-23-25-71-73-27-29-75-76-30-28-74-72-26-24-70-68-22-20-65-18-16-56-34-42(54-55-56)32-50-31-38-4-6-39(7-5-38)33-57-46(61)12-13-47(57)62/h3,8-13,34,38-39,50,58H,1-2,4-7,14-33,35-37,49H2,(H,51,59)(H,52,63)(H,53,60)/b43-3+
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| InChIKey |
MSIGFORDPQKYRT-LOVKXVSZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1082.172
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Polar area
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333.66
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Complexity
|
1873.537207
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xlogp Value
|
-0.1239
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Heavy Count
|
76
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Rot Bonds
|
46
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Hbond acc
|
24
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker