Linker Information
General Information of This Linker
| Linker ID |
LIN0OTOEH
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|---|---|---|---|---|---|---|
| Linker Name |
AsnAsnPABC
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| Linker Type |
Legumain-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H40N8O12
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| Isosmiles |
O=C(NCCOCCOCC(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CC(N)=O)C(NC1=CC=C(C=C1)CO)=O)=O)=O)=O)CCN2C(C=CC2=O)=O
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| InChI |
InChI=1S/C30H40N8O12/c31-22(40)13-20(30(48)37-21(14-23(32)41)29(47)35-19-3-1-18(16-39)2-4-19)36-25(43)15-34-26(44)17-50-12-11-49-10-8-33-24(42)7-9-38-27(45)5-6-28(38)46/h1-6,20-21,39H,7-17H2,(H2,31,40)(H2,32,41)(H,33,42)(H,34,44)(H,35,47)(H,36,43)(H,37,48)/t20-,21-/m0/s1
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| InChIKey |
ZEWOZUPROQSYFS-SFTDATJTSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
704.694
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Polar area
|
307.75
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Complexity
|
1363.587817
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xlogp Value
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-4.5815
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Heavy Count
|
50
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Rot Bonds
|
23
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Hbond acc
|
12
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker