Linker Information
General Information of This Linker
| Linker ID |
LIN0OSTJD
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| Linker Name |
CN113549127A-ADC-4-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C46H76N10O15S
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| Isosmiles |
OC([C@@H](NC([C@H](NC(OCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN1C=C(N=N1)CCCC#CC(C=N2)=CN=C2SCCC)=O)=O)C(C)C)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C46H76N10O15S/c1-4-31-72-45-50-32-37(33-51-45)9-6-5-7-10-38-34-56(55-54-38)14-16-64-18-20-66-22-24-68-26-28-70-30-29-69-27-25-67-23-21-65-19-17-63-15-13-48-40(57)35-71-46(62)53-41(36(2)3)42(58)52-39(43(59)60)11-8-12-49-44(47)61/h32-34,36,39,41H,4-5,7-8,10-31,35H2,1-3H3,(H,48,57)(H,52,58)(H,53,62)(H,59,60)(H3,47,49,61)/t39-,41+/m0/s1
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| InChIKey |
RSPREORDWUUQTF-VAASOWBASA-N
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| Pharmaceutical Properties |
Molecule Weight
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1041.236
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Polar area
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319.28
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Complexity
|
1740.046713
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xlogp Value
|
0.9623
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Heavy Count
|
72
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Rot Bonds
|
44
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Hbond acc
|
20
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker