Linker Information
General Information of This Linker
| Linker ID |
LIN0OSBNA
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| Linker Name |
CN112604004B-SCT-200-M-2-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H46N6O9
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| Isosmiles |
O=C(OCC1=CC=C(C=C1)NC(C(NC(C(NC(CC2CCC(CC2)CCN3C(C=CC3=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)O
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| InChI |
InChI=1S/C33H46N6O9/c1-20(2)29(38-26(40)18-22-7-5-21(6-8-22)15-17-39-27(41)13-14-28(39)42)31(44)37-25(4-3-16-35-32(34)45)30(43)36-24-11-9-23(10-12-24)19-48-33(46)47/h9-14,20-22,25,29H,3-8,15-19H2,1-2H3,(H,36,43)(H,37,44)(H,38,40)(H,46,47)(H3,34,35,45)
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| InChIKey |
BLAGKDBKIHBLDL-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
670.764
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Polar area
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226.33
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Complexity
|
1279.985459
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xlogp Value
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2.4054
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Heavy Count
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48
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Rot Bonds
|
17
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker