Linker Information
General Information of This Linker
| Linker ID |
LIN0OQLGY
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| Linker Name |
CN119630431A-ADC-19-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C39H43N7O10S2
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| Isosmiles |
O=C(N1CCOCCOCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NC(N)=O)=O)=O)=O)=O)=O)C(SC3=CC=CC=C3)=C(SC4=CC=CC=C4)C1=O
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| InChI |
InChI=1S/C39H43N7O10S2/c40-39(54)45-33(50)25-43-36(51)29(22-26-10-4-1-5-11-26)44-32(49)24-42-31(48)23-41-30(47)16-18-55-20-21-56-19-17-46-37(52)34(57-27-12-6-2-7-13-27)35(38(46)53)58-28-14-8-3-9-15-28/h1-15,29H,16-25H2,(H,41,47)(H,42,48)(H,43,51)(H,44,49)(H3,40,45,50,54)/t29-/m0/s1
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| InChIKey |
YMKNGVQZYAJEKI-LJAQVGFWSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
833.946
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Polar area
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244.43
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Complexity
|
1811.140756
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xlogp Value
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0.8457
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Heavy Count
|
58
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Rot Bonds
|
23
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Hbond acc
|
12
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker