Linker Information
General Information of This Linker
| Linker ID |
LIN0OPLIA
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
TW202506738A-C-039-LINKER
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C25H34N4O7
|
|||||
| Isosmiles |
CC1=CC=C(NC([C@@H](NC(CCOCCOCCNC(CCCN2C(C=CC2=O)=O)=O)=O)C)=O)C=C1
|
|||||
| InChI |
InChI=1S/C25H34N4O7/c1-18-5-7-20(8-6-18)28-25(34)19(2)27-22(31)11-14-35-16-17-36-15-12-26-21(30)4-3-13-29-23(32)9-10-24(29)33/h5-10,19H,3-4,11-17H2,1-2H3,(H,26,30)(H,27,31)(H,28,34)/t19-/m0/s1
|
|||||
| InChIKey |
DDMZKWPWUAKFIF-IBGZPJMESA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
502.568
|
Polar area
|
143.14
|
||
|
Complexity
|
885.8616306
|
xlogp Value
|
0.68292
|
|||
|
Heavy Count
|
36
|
Rot Bonds
|
16
|
|||
|
Hbond acc
|
7
|
Hbond Donor
|
3
|
|||
Each Antibody-drug Conjugate Related to This Linker