Linker Information
General Information of This Linker
| Linker ID |
LIN0OLLSL
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| Linker Name |
B-17 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H56N8O10
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| Isosmiles |
CC([C@H](NC(CCOCCOCCOCCNC(CN1C(C(C)=C(C)C(N1C)=O)=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C)C=C2)=O)=O)C
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| InChI |
InChI=1S/C36H56N8O10/c1-23(2)31(33(48)41-28(8-7-14-39-36(37)51)32(47)40-27-11-9-24(3)10-12-27)42-29(45)13-16-52-18-20-54-21-19-53-17-15-38-30(46)22-44-35(50)26(5)25(4)34(49)43(44)6/h9-12,23,28,31H,7-8,13-22H2,1-6H3,(H,38,46)(H,40,47)(H,41,48)(H,42,45)(H3,37,39,51)/t28-,31-/m0/s1
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| InChIKey |
GDRYDHWYKLXUGG-IZEXYCQBSA-N
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| Pharmaceutical Properties |
Molecule Weight
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760.89
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Polar area
|
243.21
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Complexity
|
1605.457114
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xlogp Value
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-0.25884
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Heavy Count
|
54
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Rot Bonds
|
24
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Hbond acc
|
12
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker