Linker Information
General Information of This Linker
| Linker ID |
LIN0OKLZL
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| Linker Name |
CN119317630A ADC-C5 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C23H38N4O14S
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| Isosmiles |
CC([C@H](NC(CCNC(CNC(CC(S)C(O)=O)=O)=O)=O)C(N[C@@H](COC(O1)[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO)C(O)=O)=O)C
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| InChI |
InChI=1S/C23H38N4O14S/c1-9(2)16(27-13(29)3-4-24-15(31)6-25-14(30)5-12(42)22(38)39)20(35)26-10(21(36)37)8-40-23-19(34)18(33)17(32)11(7-28)41-23/h9-12,16-19,23,28,32-34,42H,3-8H2,1-2H3,(H,24,31)(H,25,30)(H,26,35)(H,27,29)(H,36,37)(H,38,39)/t10-,11+,12?,16-,17-,18-,19+,23?/m0/s1
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| InChIKey |
FTOBXSLPJXUILM-DCFVQPMNSA-N
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| Pharmaceutical Properties |
Molecule Weight
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626.638
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Polar area
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290.38
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Complexity
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906.3228036
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xlogp Value
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-5.0913
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Heavy Count
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42
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Rot Bonds
|
17
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Hbond acc
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13
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Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker