Linker Information
General Information of This Linker
| Linker ID |
LIN0OJQRZ
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| Linker Name |
MC-Val-Ala-RG-9
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C50H75N7O16
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| Isosmiles |
O=C(N[C@@H](C)C(NC1=CC=C(COC(NCC2=CC=C(CCCOCCOCCOCCOCCOCCOCCOC)N=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C50H75N7O16/c1-36(2)45(55-42(58)11-7-6-8-20-57-43(59)18-19-44(57)60)48(62)52-37(3)47(61)54-41-15-12-38(13-16-41)35-73-49(63)51-34-39-14-17-40(53-46(39)56(4)50(64)65)10-9-21-67-24-25-69-28-29-71-32-33-72-31-30-70-27-26-68-23-22-66-5/h12-19,36-37,45H,6-11,20-35H2,1-5H3,(H,51,63)(H,52,62)(H,54,61)(H,55,58)(H,64,65)/t37-,45-/m0/s1
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| InChIKey |
BFARDDKOOXYSSO-JJXMVLQZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1030.183
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Polar area
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281.05
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Complexity
|
1935.878417
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xlogp Value
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3.3702
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Heavy Count
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73
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Rot Bonds
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39
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Hbond acc
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16
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Hbond Donor
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5
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Each Antibody-drug Conjugate Related to This Linker