Linker Information
General Information of This Linker
| Linker ID |
LIN0OHNQI
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| Linker Name |
L2-P1 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C51H80N10O20
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| Isosmiles |
CC([C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C(CN(C)C(OCC(N=N3)=CN3CCOCCOCCOCCOCCOCCOCCOCCOC)=O)=C2)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C51H80N10O20/c1-37(2)46(56-43(62)11-15-72-17-14-61-44(63)9-10-45(61)64)48(66)55-42(6-5-12-53-49(52)67)47(65)54-40-8-7-38(35-81-51(69)70)39(32-40)33-59(3)50(68)80-36-41-34-60(58-57-41)13-16-73-20-21-75-24-25-77-28-29-79-31-30-78-27-26-76-23-22-74-19-18-71-4/h7-10,32,34,37,42,46H,5-6,11-31,33,35-36H2,1-4H3,(H,54,65)(H,55,66)(H,56,62)(H,69,70)(H3,52,53,67)/t42-,46-/m0/s1
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| InChIKey |
RNSICJUJFMOPDP-HCQHVFLSSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1153.251
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Polar area
|
369.65
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Complexity
|
2130.692755
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xlogp Value
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0.3482
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Heavy Count
|
81
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Rot Bonds
|
46
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Hbond acc
|
22
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker