Linker Information
General Information of This Linker
| Linker ID |
LIN0OFOHH
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|---|---|---|---|---|---|---|
| Linker Name |
IDM-Val-Cit-PBCA
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H48F2N6O12S2
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| Isosmiles |
CC(C)[C@H](NC(=O)COCCOCCOCCOc1c(F)cc(NC(=O)/C(S)=C(/S)C(=O)O)cc1F)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
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| InChI |
InChI=1S/C36H48F2N6O12S2/c1-20(2)28(33(48)43-26(4-3-9-40-36(39)52)32(47)41-22-7-5-21(18-45)6-8-22)44-27(46)19-55-13-12-53-10-11-54-14-15-56-29-24(37)16-23(17-25(29)38)42-34(49)30(57)31(58)35(50)51/h5-8,16-17,20,26,28,45,57-58H,3-4,9-15,18-19H2,1-2H3,(H,41,47)(H,42,49)(H,43,48)(H,44,46)(H,50,51)(H3,39,40,52)/b31-30-/t26-,28-/m0/s1
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| InChIKey |
ZVCMRFMIKLFHQR-BELSCABESA-N
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| Pharmaceutical Properties |
Molecule Weight
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858.94
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Polar area
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265.97
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Complexity
|
858.2739694
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xlogp Value
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1.6928
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Heavy Count
|
58
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Rot Bonds
|
26
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Hbond acc
|
13
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Hbond Donor
|
10
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Each Antibody-drug Conjugate Related to This Linker