Linker Information
General Information of This Linker
| Linker ID |
LIN0OFAJI
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|---|---|---|---|---|---|---|
| Linker Name |
TW202506738A-C-046-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C20H30N4O8
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| Isosmiles |
O=C(N1CCCC(N[C@@H](CCC(NCCOC)=O)C(NCCCC(O)=O)=O)=O)C=CC1=O
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| InChI |
InChI=1S/C20H30N4O8/c1-32-13-11-21-15(25)7-6-14(20(31)22-10-2-5-19(29)30)23-16(26)4-3-12-24-17(27)8-9-18(24)28/h8-9,14H,2-7,10-13H2,1H3,(H,21,25)(H,22,31)(H,23,26)(H,29,30)/t14-/m0/s1
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| InChIKey |
QGXJJRDQEAWAGL-AWEZNQCLSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
454.48
|
Polar area
|
171.21
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Complexity
|
677.5499552
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xlogp Value
|
-1.2998
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Heavy Count
|
32
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Rot Bonds
|
16
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Hbond acc
|
7
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker