Linker Information
General Information of This Linker
| Linker ID |
LIN0ODAGL
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| Linker Name |
Val-Ser (beta-Glc) cleavable linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H43N5O14
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| Isosmiles |
O=C(N[C@H](C(N[C@@H](CO[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)C(NC2=CC=C(CO)C=C2)=O)=O)C(C)C)CCNC(CNC(/C=C\C(O)=O)=O)=O
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| InChI |
InChI=1S/C30H43N5O14/c1-15(2)24(35-21(39)9-10-31-22(40)11-32-20(38)7-8-23(41)42)29(47)34-18(28(46)33-17-5-3-16(12-36)4-6-17)14-48-30-27(45)26(44)25(43)19(13-37)49-30/h3-8,15,18-19,24-27,30,36-37,43-45H,9-14H2,1-2H3,(H,31,40)(H,32,38)(H,33,46)(H,34,47)(H,35,39)(H,41,42)/b8-7-/t18-,19+,24-,25+,26-,27+,30+/m0/s1
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| InChIKey |
UVNIGJNMEUUGNP-GEIASDKQSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
697.695
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Polar area
|
302.41
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Complexity
|
1259.358937
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xlogp Value
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-4.1772
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Heavy Count
|
49
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Rot Bonds
|
18
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Hbond acc
|
13
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Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker