Linker Information
General Information of This Linker
| Linker ID |
LIN0OCFNM
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|---|---|---|---|---|---|---|
| Linker Name |
CN106714844B-ADC-126-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C14H20N4O6S2
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| Isosmiles |
CN(CCN(C)C(OCC(SSC1=NC=C([N+]([O-])=O)C=C1)C)=O)C(O)=O
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| InChI |
InChI=1S/C14H20N4O6S2/c1-10(25-26-12-5-4-11(8-15-12)18(22)23)9-24-14(21)17(3)7-6-16(2)13(19)20/h4-5,8,10H,6-7,9H2,1-3H3,(H,19,20)
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| InChIKey |
OSIRTPMARUAXPI-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
404.47
|
Polar area
|
126.11
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Complexity
|
586.9692549
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xlogp Value
|
2.7968
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Heavy Count
|
26
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Rot Bonds
|
9
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Hbond acc
|
8
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Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker