Linker Information
General Information of This Linker
| Linker ID |
LIN0OAPYM
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| Linker Name |
Anti-Her2-AL1- LP2 LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C52H85N11O17
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| Isosmiles |
CC(C(NC(CCOCCOCCOCCOCCNC(CCC(C1CC(N=NN2CCOCCOCCOCCN)=C2CCCC1)=O)=O)=O)C(NC(CCCNC(N)=O)C(NC3=CC=C(C=C3)COC(NCC(O)=O)=O)=O)=O)C
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| InChI |
InChI=1S/C52H85N11O17/c1-37(2)48(50(70)59-41(7-5-17-56-51(54)71)49(69)58-40-11-9-38(10-12-40)36-80-52(72)57-35-47(67)68)60-46(66)15-20-73-24-28-77-32-33-79-30-26-75-22-18-55-45(65)14-13-44(64)39-6-3-4-8-43-42(34-39)61-62-63(43)19-23-76-27-31-78-29-25-74-21-16-53/h9-12,37,39,41,48H,3-8,13-36,53H2,1-2H3,(H,55,65)(H,57,72)(H,58,69)(H,59,70)(H,60,66)(H,67,68)(H3,54,56,71)
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| InChIKey |
OUHYAMQMADSTQJ-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1136.312
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Polar area
|
385.56
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Complexity
|
2048.69226
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xlogp Value
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0.1173
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Heavy Count
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80
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Rot Bonds
|
44
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Hbond acc
|
20
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker