Linker Information
General Information of This Linker
| Linker ID |
LIN0NUHPD
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| Linker Name |
Daratumumab-I-30-0.22 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C60H78FN11O17
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| Isosmiles |
CC(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@@H](CC1=CNC=N1)C(N[C@H](C(NCCOCCNC(C2=CC=C(OC(CCOCCOCCOCCOCCOCCOCCN)=O)C(F)=C2)=O)=O)CC3=CNC4=C3C=CC=C4)=O)=O)CC5=CNC6=C5C=CC=C6)=O)=O
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| InChI |
InChI=1S/C60H78FN11O17/c1-39(73)69-52(34-54(74)75)60(81)71-50(32-42-36-67-48-9-5-3-7-45(42)48)58(79)72-51(33-43-37-63-38-68-43)59(80)70-49(31-41-35-66-47-8-4-2-6-44(41)47)57(78)65-15-19-84-18-14-64-56(77)40-10-11-53(46(61)30-40)89-55(76)12-16-82-20-22-85-24-26-87-28-29-88-27-25-86-23-21-83-17-13-62/h2-11,30,35-38,49-52,66-67H,12-29,31-34,62H2,1H3,(H,63,68)(H,64,77)(H,65,78)(H,69,73)(H,70,80)(H,71,81)(H,72,79)(H,74,75)/t49-,50-,51-,52-/m0/s1
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| InChIKey |
AHMOSWDOAHEXER-CFOCFGCLSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1244.342
|
Polar area
|
389.09
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Complexity
|
3066.412941
|
xlogp Value
|
0.8897
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Heavy Count
|
89
|
Rot Bonds
|
44
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Hbond acc
|
18
|
Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker