Linker Information
General Information of This Linker
| Linker ID |
LIN0NSMYT
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|---|---|---|---|---|---|---|
| Linker Name |
C5-VC-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C23H36N6O6
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| Isosmiles |
CC([C@H](NC(CCCC(N)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(C=C1)CO)=O)=O)C
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| InChI |
InChI=1S/C23H36N6O6/c1-14(2)20(29-19(32)7-3-6-18(24)31)22(34)28-17(5-4-12-26-23(25)35)21(33)27-16-10-8-15(13-30)9-11-16/h8-11,14,17,20,30H,3-7,12-13H2,1-2H3,(H2,24,31)(H,27,33)(H,28,34)(H,29,32)(H3,25,26,35)/t17-,20-/m0/s1
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| InChIKey |
NWEBVMZBGOALHI-PXNSSMCTSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
492.577
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Polar area
|
205.74
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Complexity
|
829.2942158
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xlogp Value
|
-0.1529
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Heavy Count
|
35
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Rot Bonds
|
15
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Hbond acc
|
6
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker