Linker Information
General Information of This Linker
| Linker ID |
LIN0NRNJH
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|---|---|---|---|---|---|---|
| Name |
Mal-PEG8-Val-Cit-PEG8-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C47H77N7O16
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(NC2=CC=C(CO)C=C2)=O)=O)=O)C
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| InChI |
InChI=1S/C47H77N7O16/c1-36(2)44(53-40(56)8-4-3-5-18-54-42(58)13-14-43(54)59)46(61)52-39(7-6-16-50-47(48)62)45(60)49-17-20-64-22-24-66-26-28-68-30-32-70-34-33-69-31-29-67-27-25-65-23-21-63-19-15-41(57)51-38-11-9-37(35-55)10-12-38/h9-14,36,39,44,55H,3-8,15-35H2,1-2H3,(H,49,60)(H,51,57)(H,52,61)(H,53,56)(H3,48,50,62)/t39-,44-/m0/s1
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| InChIKey |
DAGNFOQOSBZEEY-LWOWNENESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
996.166
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Polar area
|
302.97
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Complexity
|
1584.814942
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xlogp Value
|
0.316
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Heavy Count
|
70
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Rot Bonds
|
44
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Hbond acc
|
16
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker