Linker Information
General Information of This Linker
| Linker ID |
LIN0NPAPC
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| Linker Name |
CN116137818A-AbT-EXP24-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H40N6O12S
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC(S(=O)(O)=O)=C(C=C2)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C29H40N6O12S/c1-17(2)25(34-22(36)8-4-3-5-14-35-23(37)11-12-24(35)38)27(40)33-20(7-6-13-31-28(30)41)26(39)32-19-10-9-18(16-47-29(42)43)21(15-19)48(44,45)46/h9-12,15,17,20,25H,3-8,13-14,16H2,1-2H3,(H,32,39)(H,33,40)(H,34,36)(H,42,43)(H3,30,31,41)(H,44,45,46)/t20-,25-/m0/s1
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| InChIKey |
RSBYUDGEOFBIFG-CPJSRVTESA-N
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| Pharmaceutical Properties |
Molecule Weight
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696.736
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Polar area
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280.7
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Complexity
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1441.354991
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xlogp Value
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0.6259
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Heavy Count
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48
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Rot Bonds
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19
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Hbond acc
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10
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Hbond Donor
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7
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Each Antibody-drug Conjugate Related to This Linker