Linker Information
General Information of This Linker
| Linker ID |
LIN0NNLVG
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| Linker Name |
CN113549127A-ADC-2-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C31H51N7O8S
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| Isosmiles |
CCCSC1=NC(CN2CCCOCCOCCCCCC(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CCCNC(N)=O)=O)=O)=C(C2=O)C=N1
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| InChI |
InChI=1S/C31H51N7O8S/c1-4-18-47-31-34-19-22-24(36-31)20-38(28(22)41)13-9-15-46-17-16-45-14-7-5-6-11-25(39)37-26(21(2)3)27(40)35-23(29(42)43)10-8-12-33-30(32)44/h19,21,23,26H,4-18,20H2,1-3H3,(H,35,40)(H,37,39)(H,42,43)(H3,32,33,44)/t23-,26-/m0/s1
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| InChIKey |
YOIPLOAIVOBUSQ-OZXSUGGESA-N
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| Pharmaceutical Properties |
Molecule Weight
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681.857
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Polar area
|
215.17
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Complexity
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1108.847535
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xlogp Value
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2.0769
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Heavy Count
|
47
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Rot Bonds
|
25
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Hbond acc
|
10
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker