Linker Information
General Information of This Linker
| Linker ID |
LIN0NMUAN
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| Linker Name |
CN116137818A-AbT-EXP14-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H38N6O11S
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| Isosmiles |
CC([C@@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C(S(=O)(O)=O)=C2)CO)=O)=O)C
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| InChI |
InChI=1S/C27H38N6O11S/c1-16(2)24(32-21(35)9-12-44-13-11-33-22(36)7-8-23(33)37)26(39)31-19(4-3-10-29-27(28)40)25(38)30-18-6-5-17(15-34)20(14-18)45(41,42)43/h5-8,14,16,19,24,34H,3-4,9-13,15H2,1-2H3,(H,30,38)(H,31,39)(H,32,35)(H3,28,29,40)(H,41,42,43)/t19-,24+/m0/s1
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| InChIKey |
OTELJMGUFWYPPF-YADARESESA-N
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| Pharmaceutical Properties |
Molecule Weight
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654.699
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Polar area
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263.63
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Complexity
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1330.359864
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xlogp Value
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-1.2301
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Heavy Count
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45
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Rot Bonds
|
18
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Hbond acc
|
10
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker