Linker Information
General Information of This Linker
| Linker ID |
LIN0NLGOR
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
DIBAC-suC-PEG12
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C46H69N5O16
|
|||||
| Isosmiles |
O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCC(N(C(C=CC=C1)=C1C2=C3NN=N2)CC4=C3C=CC=C4)=O)=O
|
|||||
| InChI |
InChI=1S/C46H69N5O16/c52-42(9-10-43(53)51-37-38-5-1-2-6-39(38)45-46(49-50-48-45)40-7-3-4-8-41(40)51)47-12-14-57-16-18-59-20-22-61-24-26-63-28-30-65-32-34-67-36-35-66-33-31-64-29-27-62-25-23-60-21-19-58-17-15-56-13-11-44(54)55/h1-8H,9-37H2,(H,47,52)(H,54,55)(H,48,49,50)
|
|||||
| InChIKey |
FTXQBMHRRMUCMF-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
948.077
|
Polar area
|
239.04
|
||
|
Complexity
|
1693.703079
|
xlogp Value
|
2.5556
|
|||
|
Heavy Count
|
67
|
Rot Bonds
|
42
|
|||
|
Hbond acc
|
17
|
Hbond Donor
|
3
|
|||
Each Antibody-drug Conjugate Related to This Linker