Linker Information
General Information of This Linker
| Linker ID |
LIN0NLELZ
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| Linker Name |
TW202506738A-C-168-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C26H29N5O7
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| Isosmiles |
C[C@H](NC(CCC(N(CCN(C1=O)C(C=C1)=O)CCN2C(C=CC2=O)=O)=O)=O)C(NC(C=C3)=CC=C3C)=O
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| InChI |
InChI=1S/C26H29N5O7/c1-17-3-5-19(6-4-17)28-26(38)18(2)27-20(32)7-8-21(33)29(13-15-30-22(34)9-10-23(30)35)14-16-31-24(36)11-12-25(31)37/h3-6,9-12,18H,7-8,13-16H2,1-2H3,(H,27,32)(H,28,38)/t18-/m0/s1
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| InChIKey |
NRQDRACSJUZVLF-SFHVURJKSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
523.546
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Polar area
|
153.27
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Complexity
|
1076.895094
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xlogp Value
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-0.10298
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Heavy Count
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38
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Rot Bonds
|
12
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Hbond acc
|
7
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker