Linker Information
General Information of This Linker
| Linker ID |
LIN0NJZWY
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| Linker Name |
LC1 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C18H14F5NO4
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| Isosmiles |
O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)C2CCC(CN3C(C=CC3=O)=O)CC2
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| PubChem CID | ||||||
| InChI |
InChI=1S/C18H14F5NO4/c19-12-13(20)15(22)17(16(23)14(12)21)28-18(27)9-3-1-8(2-4-9)7-24-10(25)5-6-11(24)26/h5-6,8-9H,1-4,7H2
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| InChIKey |
TZWWHJCDRYTGLJ-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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403.303
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Polar area
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63.68
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Complexity
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790.2746658
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xlogp Value
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3.0189
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Heavy Count
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28
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Rot Bonds
|
4
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Hbond acc
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4
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Hbond Donor
|
0
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Each Antibody-drug Conjugate Related to This Linker