Linker Information
General Information of This Linker
| Linker ID |
LIN0NIQNH
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|---|---|---|---|---|---|---|
| Linker Name |
LT4212552T-ADC-17-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C22H25N5O8
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| Isosmiles |
O=C(NCC(O)=O)[C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCN2C(C=CC2=O)=O)=O)=O)=O
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| InChI |
InChI=1S/C22H25N5O8/c28-16(8-9-27-19(31)6-7-20(27)32)23-11-17(29)24-12-18(30)26-15(22(35)25-13-21(33)34)10-14-4-2-1-3-5-14/h1-7,15H,8-13H2,(H,23,28)(H,24,29)(H,25,35)(H,26,30)(H,33,34)/t15-/m0/s1
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| InChIKey |
AKDOBVGZPKERON-HNNXBMFYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
487.469
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Polar area
|
191.08
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Complexity
|
960.1244653
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xlogp Value
|
-2.5378
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Heavy Count
|
35
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Rot Bonds
|
13
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Hbond acc
|
7
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker