Linker Information
General Information of This Linker
| Linker ID |
LIN0NGTMH
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Mal-PEG12-Val-Cit-PABC
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C48H80N6O19
|
|||||
| Isosmiles |
CC(C)C(NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(O)cc1
|
|||||
| InChI |
InChI=1S/C48H80N6O19/c1-38(2)45(47(60)52-41(4-3-12-50-48(49)61)46(59)51-39-5-7-40(55)8-6-39)53-42(56)11-14-62-16-18-64-20-22-66-24-26-68-28-30-70-32-34-72-36-37-73-35-33-71-31-29-69-27-25-67-23-21-65-19-17-63-15-13-54-43(57)9-10-44(54)58/h5-10,38,41,45,55H,3-4,11-37H2,1-2H3,(H,51,59)(H,52,60)(H,53,56)(H3,49,50,61)
|
|||||
| InChIKey |
LRYIIAWURANRSW-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
1045.191
|
Polar area
|
310.79
|
||
|
Complexity
|
73
|
xlogp Value
|
-0.0809
|
|||
|
Heavy Count
|
73
|
Rot Bonds
|
49
|
|||
|
Hbond acc
|
19
|
Hbond Donor
|
6
|
|||
Each Antibody-drug Conjugate Related to This Linker
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.