Linker Information
General Information of This Linker
| Linker ID |
LIN0NEWKD
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| Linker Name |
T-124 linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C42H63N5O20
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| Isosmiles |
CN(CCOCCOCCOCCN1C=C(N=N1)CCOCCOCCOCCOCCOCCOCCN(C(C=C2)=O)C2=O)C(C3=CC=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](O4)C(O)=O)C(O)=C3)=O
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| InChI |
InChI=1S/C42H63N5O20/c1-45(40(54)30-2-3-33(32(48)28-30)66-42-38(53)36(51)37(52)39(67-42)41(55)56)7-11-58-15-19-62-20-16-59-12-8-46-29-31(43-44-46)6-10-57-14-18-61-22-24-64-26-27-65-25-23-63-21-17-60-13-9-47-34(49)4-5-35(47)50/h2-5,28-29,36-39,42,48,51-53H,6-27H2,1H3,(H,55,56)/t36-,37-,38+,39-,42+/m0/s1
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| InChIKey |
MLDHLCWCZMLNOT-PLYXSNNKSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
957.981
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Polar area
|
308.15
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Complexity
|
1703.125191
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xlogp Value
|
-2.3562
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Heavy Count
|
67
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Rot Bonds
|
37
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Hbond acc
|
22
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker