General Information of This Linker
Linker ID
LIN0NEUFF
Linker Name
M-Gly-Ala
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C9H11N3O4
Isosmiles
C[C@H](NC(CN1C(C=CC1=O)=O)=O)C(N)=O
InChI
InChI=1S/C9H11N3O4/c1-5(9(10)16)11-6(13)4-12-7(14)2-3-8(12)15/h2-3,5H,4H2,1H3,(H2,10,16)(H,11,13)/t5-/m0/s1
InChIKey
SRCNPOCVLRHDAF-YFKPBYRVSA-N
Pharmaceutical Properties
Molecule Weight
225.204
Polar area
109.57
Complexity
347.4995491
xlogp Value
-2.0986
Heavy Count
16
Rot Bonds
4
Hbond acc
4
Hbond Donor
2
Each Antibody-drug Conjugate Related to This Linker