Linker Information
General Information of This Linker
| Linker ID |
LIN0NDFPC
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|---|---|---|---|---|---|---|
| Linker Name |
Daratumumab-I-21-0.18 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C66H109N13O23
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| Isosmiles |
NC(NCCC[C@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(C(C=C1)=CC=C1OC(CCOCCOCCOCCOCCOCCOCCN)=O)=O)=O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC2=CNC3=C2C=CC=C3)C(O)=O)=O)=O)=O)=N
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| InChI |
InChI=1S/C66H109N13O23/c67-15-21-90-25-29-94-33-37-98-41-39-97-36-32-93-28-24-89-20-14-60(82)102-52-11-9-50(10-12-52)61(83)72-18-22-91-26-30-95-34-38-99-42-44-101-46-45-100-43-40-96-35-31-92-27-23-88-19-13-58(80)77-56(8-4-17-74-66(70)71)63(85)79-55(7-3-16-73-65(68)69)62(84)76-49-59(81)78-57(64(86)87)47-51-48-75-54-6-2-1-5-53(51)54/h1-2,5-6,9-12,48,55-57,75H,3-4,7-8,13-47,49,67H2,(H,72,83)(H,76,84)(H,77,80)(H,78,81)(H,79,85)(H,86,87)(H4,68,69,73)(H4,70,71,74)/t55-,56-,57-/m0/s1
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| InChIKey |
NDIUCDUERKHDRY-BSNUEQINSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1452.666
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Polar area
|
503.93
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Complexity
|
2646.228705
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xlogp Value
|
-1.80116
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Heavy Count
|
102
|
Rot Bonds
|
67
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Hbond acc
|
25
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Hbond Donor
|
14
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Each Antibody-drug Conjugate Related to This Linker