Linker Information
General Information of This Linker
| Linker ID |
LIN0NBCEQ
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| Linker Name |
CN113549127A-ADC-5-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C45H76N8O16S
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| Isosmiles |
OC([C@@H](NC([C@@H](NC(OCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC#CC1=CN=C(SCCC)N=C1)=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C45H76N8O16S/c1-4-31-70-44-50-32-36(33-51-44)9-6-5-7-11-38(54)47-13-15-61-17-19-63-21-23-65-25-27-67-29-30-68-28-26-66-24-22-64-20-18-62-16-14-48-39(55)34-69-45(60)53-40(35(2)3)41(56)52-37(42(57)58)10-8-12-49-43(46)59/h32-33,35,37,40H,4-5,7-8,10-31,34H2,1-3H3,(H,47,54)(H,48,55)(H,52,56)(H,53,60)(H,57,58)(H3,46,49,59)/t37-,40-/m0/s1
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| InChIKey |
MZZQQOGDYAMXJB-DFUITMLUSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1017.21
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Polar area
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317.67
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Complexity
|
1546.507265
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xlogp Value
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0.6344
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Heavy Count
|
70
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Rot Bonds
|
44
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Hbond acc
|
18
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker