Linker Information
General Information of This Linker
| Linker ID |
LIN0NALXO
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| Linker Name |
CN113874046B-ADC-6-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H54N8O7
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| Isosmiles |
CNN(CC1=CC2=CC=CN=C2N1CCC(N3CCC(NCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(O)=O)=O)=O)CC3)=O)C
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| InChI |
InChI=1S/C33H54N8O7/c1-23(2)30(32(44)37-24(3)33(45)46)38-28(42)11-17-47-19-20-48-18-13-35-26-8-14-40(15-9-26)29(43)10-16-41-27(22-39(5)34-4)21-25-7-6-12-36-31(25)41/h6-7,12,21,23-24,26,30,34-35H,8-11,13-20,22H2,1-5H3,(H,37,44)(H,38,42)(H,45,46)/t24-,30-/m0/s1
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| InChIKey |
YIVHKBZEKXEADZ-NGQVCNFZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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674.844
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Polar area
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179.39
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Complexity
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1270.347547
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xlogp Value
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0.7266
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Heavy Count
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48
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Rot Bonds
|
21
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Hbond acc
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11
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker