Linker Information
General Information of This Linker
| Linker ID |
LIN0MUXBI
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|---|---|---|---|---|---|---|
| Linker Name |
Mal-Val-Cit-PABC-DMEA-PEG2
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H56N8O10
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| Isosmiles |
CC(C)C(NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)N(C)CCNCCOCCO)cc1
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| InChI |
InChI=1S/C36H56N8O10/c1-25(2)32(42-29(46)9-5-4-6-19-44-30(47)14-15-31(44)48)34(50)41-28(8-7-16-39-35(37)51)33(49)40-27-12-10-26(11-13-27)24-54-36(52)43(3)20-17-38-18-22-53-23-21-45/h10-15,25,28,32,38,45H,4-9,16-24H2,1-3H3,(H,40,49)(H,41,50)(H,42,46)(H3,37,39,51)
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| InChIKey |
QAGRPIUQRXCKLP-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
760.89
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Polar area
|
250.83
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Complexity
|
54
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xlogp Value
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0.3515
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Heavy Count
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54
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Rot Bonds
|
26
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker
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