Linker Information
General Information of This Linker
| Linker ID |
LIN0MTCNO
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
WO2024105205A1-5e-9476-Linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C15H25N5O7
|
|||||
| Isosmiles |
O=C(O)[C@@H](NC([C@H](NC([C@H](C)NC(CCCC(N)=O)=O)=O)C)=O)CC(N)=O
|
|||||
| InChI |
InChI=1S/C15H25N5O7/c1-7(18-12(23)5-3-4-10(16)21)13(24)19-8(2)14(25)20-9(15(26)27)6-11(17)22/h7-9H,3-6H2,1-2H3,(H2,16,21)(H2,17,22)(H,18,23)(H,19,24)(H,20,25)(H,26,27)/t7-,8+,9-/m0/s1
|
|||||
| InChIKey |
SXUZPDBMHLVLNT-YIZRAAEISA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
387.393
|
Polar area
|
210.78
|
||
|
Complexity
|
568.8457307
|
xlogp Value
|
-2.9038
|
|||
|
Heavy Count
|
27
|
Rot Bonds
|
12
|
|||
|
Hbond acc
|
6
|
Hbond Donor
|
6
|
|||
Each Antibody-drug Conjugate Related to This Linker