Linker Information
General Information of This Linker
| Linker ID |
LIN0MRMBM
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| Linker Name |
DBCO-AA-PEG13-AAN
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C69H105N7O22
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| Isosmiles |
O=C(N(CC1)CCC1(CC2)CCC2C(NCCC(N3CC4=C(C#CC5=C3C=CC=C5)C=CC=C4)=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@H](C(N[C@@H](C)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)C)=O
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| InChI |
InChI=1S/C69H105N7O22/c1-53(65(81)73-54(2)66(82)74-59(68(84)85)51-61(70)77)72-62(78)16-25-86-27-29-88-31-33-90-35-37-92-39-41-94-43-45-96-47-49-98-50-48-97-46-44-95-42-40-93-38-36-91-34-32-89-30-28-87-26-17-63(79)75-23-20-69(21-24-75)18-13-57(14-19-69)67(83)71-22-15-64(80)76-52-58-9-4-3-7-55(58)11-12-56-8-5-6-10-60(56)76/h3-10,53-54,57,59H,13-52H2,1-2H3,(H2,70,77)(H,71,83)(H,72,78)(H,73,81)(H,74,82)(H,84,85)/t53-,54-,59-/m0/s1
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| InChIKey |
KXJDABBALJHHTA-FVENHMIHSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1384.626
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Polar area
|
357.4
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Complexity
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2625.384224
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xlogp Value
|
1.6885
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Heavy Count
|
98
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Rot Bonds
|
54
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Hbond acc
|
21
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker