Linker Information
General Information of This Linker
| Linker ID |
LIN0MQPEI
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|---|---|---|---|---|---|---|
| Linker Name |
MC-Ala-Ala-RG-6
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H43N7O9
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| Isosmiles |
O=C(N[C@@H](C)C(NC1=CC=C(COC(NCC2=CC=CN=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C34H43N7O9/c1-21(2)29(39-26(42)10-6-5-7-18-41-27(43)15-16-28(41)44)32(46)37-22(3)31(45)38-25-13-11-23(12-14-25)20-50-33(47)36-19-24-9-8-17-35-30(24)40(4)34(48)49/h8-9,11-17,21-22,29H,5-7,10,18-20H2,1-4H3,(H,36,47)(H,37,46)(H,38,45)(H,39,42)(H,48,49)/t22-,29-/m0/s1
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| InChIKey |
CZTWVYVFRBOGPU-ZTOMLWHTSA-N
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| Pharmaceutical Properties |
Molecule Weight
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693.758
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Polar area
|
216.44
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Complexity
|
1514.491626
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xlogp Value
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2.6916
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Heavy Count
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50
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Rot Bonds
|
17
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Hbond acc
|
9
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker