Linker Information
General Information of This Linker
| Linker ID |
LIN0MLZFR
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| Linker Name |
Linker of ADC2-54
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H50N8O15S
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| Isosmiles |
O=C(NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(O)=O)=O)=O)=O)[C@@H](NC(CCCCCN2C(C=CC2=O)=O)=O)CCC(NC[C@H](O3)[C@H](O)[C@@H](O)[C@H](O)[C@H]3C(N)=O)=O.[S]
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| InChI |
InChI=1S/C37H50N8O15.S/c38-35(57)34-33(56)32(55)31(54)23(60-34)16-39-24(46)11-10-21(43-25(47)9-5-2-6-14-45-28(50)12-13-29(45)51)36(58)41-17-26(48)40-18-27(49)44-22(37(59)42-19-30(52)53)15-20-7-3-1-4-8-20;/h1,3-4,7-8,12-13,21-23,31-34,54-56H,2,5-6,9-11,14-19H2,(H2,38,57)(H,39,46)(H,40,48)(H,41,58)(H,42,59)(H,43,47)(H,44,49)(H,52,53);/t21-,22-,23-,31-,32+,33-,34-;/m0./s1
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| InChIKey |
YPUNSEUUKKTOMA-ATBTVJFESA-N
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| Pharmaceutical Properties |
Molecule Weight
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878.915
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Polar area
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362.29
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Complexity
|
1680.29589
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xlogp Value
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-5.0027
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Heavy Count
|
61
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Rot Bonds
|
24
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Hbond acc
|
14
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Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker