Linker Information
General Information of This Linker
| Linker ID |
LIN0MKIAH
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| Linker Name |
CN119630431A-ADC-76-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H52N8O10
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| Isosmiles |
CN(CCNC)C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCN2C(C=CC2=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1)=O
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| InChI |
InChI=1S/C34H52N8O10/c1-23(2)30(40-27(43)13-18-50-20-21-51-19-17-42-28(44)11-12-29(42)45)32(47)39-26(6-5-14-37-33(35)48)31(46)38-25-9-7-24(8-10-25)22-52-34(49)41(4)16-15-36-3/h7-12,23,26,30,36H,5-6,13-22H2,1-4H3,(H,38,46)(H,39,47)(H,40,43)(H3,35,37,48)/t26-,30-/m0/s1
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| InChIKey |
VEBJLRWHFBRYMD-YZNIXAGQSA-N
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| Pharmaceutical Properties |
Molecule Weight
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732.836
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Polar area
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239.83
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Complexity
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1304.250834
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xlogp Value
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-0.1647
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Heavy Count
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52
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Rot Bonds
|
24
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Hbond acc
|
11
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker