Linker Information
General Information of This Linker
| Linker ID |
LIN0MJLJY
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| Linker Name |
MP-Ala-Ala-RG-1
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H34N6O9
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| Isosmiles |
O=C(N[C@@H](C)C(NC1=CC=C(COC(NCC2=CC=CC=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C)NC(CCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C30H34N6O9/c1-18(32-24(37)14-15-36-25(38)12-13-26(36)39)27(40)33-19(2)28(41)34-22-10-8-20(9-11-22)17-45-29(42)31-16-21-6-4-5-7-23(21)35(3)30(43)44/h4-13,18-19H,14-17H2,1-3H3,(H,31,42)(H,32,37)(H,33,40)(H,34,41)(H,43,44)/t18-,19-/m0/s1
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| InChIKey |
MYVUBJXOLPCFNR-OALUTQOASA-N
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| Pharmaceutical Properties |
Molecule Weight
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622.635
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Polar area
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203.55
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Complexity
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1417.110821
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xlogp Value
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1.4902
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Heavy Count
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45
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Rot Bonds
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13
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Hbond acc
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8
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Hbond Donor
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5
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Each Antibody-drug Conjugate Related to This Linker