Linker Information
General Information of This Linker
| Linker ID |
LIN0MITZV
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| Linker Name |
CN117362435A+CD44-SN-38+Linker
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| Linker Type |
Uncleavable linker
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| Antibody-Linker Relation |
Uncleavable
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| Structure |
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| Formula |
C43H72N8O16
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| Isosmiles |
OC([C@@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN1C=C(N=N1)CNC(C2CCC(CN3C(C=CC3=O)=O)CC2)=O)=O)=O)CCCCN)=O
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| InChI |
InChI=1S/C43H72N8O16/c44-10-2-1-3-37(43(57)58)47-39(53)33-67-32-38(52)45-11-13-59-15-17-61-19-21-63-23-25-65-27-28-66-26-24-64-22-20-62-18-16-60-14-12-50-31-36(48-49-50)29-46-42(56)35-6-4-34(5-7-35)30-51-40(54)8-9-41(51)55/h8-9,31,34-35,37H,1-7,10-30,32-33,44H2,(H,45,52)(H,46,56)(H,47,53)(H,57,58)/t34?,35?,37-/m0/s1
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| InChIKey |
JQIVKVQIDOKWNG-RWCHMDSTSA-N
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| Pharmaceutical Properties |
Molecule Weight
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957.089
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Polar area
|
301.78
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Complexity
|
1491.949781
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xlogp Value
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-1.4103
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Heavy Count
|
67
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Rot Bonds
|
42
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Hbond acc
|
19
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker