General Information of This Linker
Linker ID
LIN0MGGRW
Linker Name
NHS ester linker
Linker Type
Uncleavable linker
Antibody-Linker Relation
Uncleavable
Structure
Formula
C10H14N2O4
Isosmiles
O=C1C=CC(N1OC(CCCCCN)=O)=O
InChI
InChI=1S/C10H14N2O4/c11-7-3-1-2-4-10(15)16-12-8(13)5-6-9(12)14/h5-6H,1-4,7,11H2
InChIKey
NMAARCUHGOKLHN-UHFFFAOYSA-N
Pharmaceutical Properties
Molecule Weight
226.232
Polar area
89.7
Complexity
286
xlogp Value
-0.1113
Heavy Count
16
Rot Bonds
6
Hbond acc
5
Hbond Donor
1
Each Antibody-drug Conjugate Related to This Linker