Linker Information
General Information of This Linker
| Linker ID |
LIN0MDVFB
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| Linker Name |
Tumor microenviroment activable tripeptide linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H49N7O4
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| Isosmiles |
CCCN(CCC)CCCC[C@H](NC(=O)C(NC(=O)CCCC#Cc1cncnc1)C(C)C)C(=O)NCC(=O)NC
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| InChI |
InChI=1S/C30H49N7O4/c1-6-16-37(17-7-2)18-12-11-14-25(29(40)34-21-27(39)31-5)35-30(41)28(23(3)4)36-26(38)15-10-8-9-13-24-19-32-22-33-20-24/h19-20,22-23,25,28H,6-8,10-12,14-18,21H2,1-5H3,(H,31,39)(H,34,40)(H,35,41)(H,36,38)/t25-,28?/m0/s1
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| InChIKey |
UCKQGMHUWMMEIM-ALLRNTDFSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
571.767
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Polar area
|
145.42
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Complexity
|
571.384603
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xlogp Value
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1.7785
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Heavy Count
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41
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Rot Bonds
|
19
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Hbond acc
|
7
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker