Linker Information
General Information of This Linker
| Linker ID |
LIN0MBSTK
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| Linker Name |
TW202506738A-C-020-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H42N6O8
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| Isosmiles |
C[C@H](NC(CCCNC([C@@H](NC(CCCN1C(C=CC1=O)=O)=O)CCC(NCCOC)=O)=O)=O)C(NC2=CC=C(C)C=C2)=O
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| InChI |
InChI=1S/C30H42N6O8/c1-20-8-10-22(11-9-20)34-29(42)21(2)33-25(38)6-4-16-32-30(43)23(12-13-24(37)31-17-19-44-3)35-26(39)7-5-18-36-27(40)14-15-28(36)41/h8-11,14-15,21,23H,4-7,12-13,16-19H2,1-3H3,(H,31,37)(H,32,43)(H,33,38)(H,34,42)(H,35,39)/t21-,23-/m0/s1
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| InChIKey |
CUHYEOXPAXBPQR-GMAHTHKFSA-N
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| Pharmaceutical Properties |
Molecule Weight
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614.7
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Polar area
|
192.11
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Complexity
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1144.895094
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xlogp Value
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0.06742
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Heavy Count
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44
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Rot Bonds
|
19
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Hbond acc
|
8
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker