Linker Information
General Information of This Linker
| Linker ID |
LIN0MANKF
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| Linker Name |
CN119317630A ADC-C7 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H37N3O13
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(CCC1=O)=O)=O)C(N[C@@H](CO[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O2)C(O)=O)=O)C
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| InChI |
InChI=1S/C24H37N3O13/c1-11(2)16(26-13(28)6-4-3-5-9-27-14(29)7-8-15(27)30)21(34)25-12(22(35)36)10-39-24-19(33)17(31)18(32)20(40-24)23(37)38/h11-12,16-20,24,31-33H,3-10H2,1-2H3,(H,25,34)(H,26,28)(H,35,36)(H,37,38)/t12-,16-,17-,18-,19+,20-,24+/m0/s1
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| InChIKey |
RRPHHKHSFGZSEY-SEINCZPMSA-N
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| Pharmaceutical Properties |
Molecule Weight
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575.568
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Polar area
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249.33
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Complexity
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892.3228036
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xlogp Value
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-2.6852
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Heavy Count
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40
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Rot Bonds
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15
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker