Linker Information
General Information of This Linker
| Linker ID |
LIN0MANAU
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| Linker Name |
CN116137818A-AbT-EXP28-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H38Br2N6O12S
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(C(Br)=C(Br)C1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC(S(=O)(O)=O)=C(C=C2)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C29H38Br2N6O12S/c1-15(2)23(36-20(38)8-4-3-5-12-37-26(41)21(30)22(31)27(37)42)25(40)35-18(7-6-11-33-28(32)43)24(39)34-17-10-9-16(14-49-29(44)45)19(13-17)50(46,47)48/h9-10,13,15,18,23H,3-8,11-12,14H2,1-2H3,(H,34,39)(H,35,40)(H,36,38)(H,44,45)(H3,32,33,43)(H,46,47,48)/t18-,23-/m0/s1
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| InChIKey |
HLAOPARSBDVSBS-MBSDFSHPSA-N
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| Pharmaceutical Properties |
Molecule Weight
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854.528
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Polar area
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280.7
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Complexity
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1530.923814
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xlogp Value
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2.0711
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Heavy Count
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50
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Rot Bonds
|
19
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Hbond acc
|
10
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker