Linker Information
General Information of This Linker
| Linker ID |
LIN0LYKDA
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Mal-Polysarcosine10-Val-Ala-PABC
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C66H101N17O23
|
|||||
| Isosmiles |
CC(=O)N[C@@H](C(=O)N[C@@H](C)C(=O)Nc1ccc([C@H](O)CNC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)CCN2C(=O)C=CC2=O)C(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)N(C)CC(=O)O)cc1)C(C)C
|
|||||
| InChI |
InChI=1S/C66H101N17O23/c1-41(2)63(70-43(4)84)65(103)69-42(3)64(102)71-45-17-15-44(16-18-45)47(85)29-68-48(86)20-19-46(72-50(88)40-106-28-27-105-26-24-67-49(87)23-25-83-51(89)21-22-52(83)90)66(104)82(14)38-61(99)80(12)36-59(97)78(10)34-57(95)76(8)32-55(93)74(6)30-53(91)73(5)31-54(92)75(7)33-56(94)77(9)35-58(96)79(11)37-60(98)81(13)39-62(100)101/h15-18,21-22,41-42,46-47,63,85H,19-20,23-40H2,1-14H3,(H,67,87)(H,68,86)(H,69,103)(H,70,84)(H,71,102)(H,72,88)(H,100,101)/t42-,46-,47+,63+/m0/s1
|
|||||
| InChIKey |
PCCLPSVEKLLVFX-GYSXZTFUSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
1500.63
|
Polar area
|
491.07
|
||
|
Complexity
|
1499.725622
|
xlogp Value
|
-7.1618
|
|||
|
Heavy Count
|
106
|
Rot Bonds
|
45
|
|||
|
Hbond acc
|
22
|
Hbond Donor
|
8
|
|||
Each Antibody-drug Conjugate Related to This Linker