Linker Information
General Information of This Linker
| Linker ID |
LIN0LWEAO
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| Linker Name |
US20220378928A1 C-21 Linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C31H37F3N6O10
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| Isosmiles |
O=C(NCO[C@H](C(F)(F)F)C(O)=O)CNC([C@@H](NC(CNC(CNC(C1CCC(CN2C(C=CC2=O)=O)CC1)=O)=O)=O)CC3=CC=CC=C3)=O
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| InChI |
InChI=1S/C31H37F3N6O10/c32-31(33,34)27(30(48)49)50-17-38-23(42)14-37-29(47)21(12-18-4-2-1-3-5-18)39-24(43)15-35-22(41)13-36-28(46)20-8-6-19(7-9-20)16-40-25(44)10-11-26(40)45/h1-5,10-11,19-21,27H,6-9,12-17H2,(H,35,41)(H,36,46)(H,37,47)(H,38,42)(H,39,43)(H,48,49)/t19?,20?,21-,27-/m0/s1
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| InChIKey |
DHSONNJZKXBYQN-OJCYEVBQSA-N
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| Pharmaceutical Properties |
Molecule Weight
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710.663
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Polar area
|
229.41
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Complexity
|
1371.234755
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xlogp Value
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-1.1003
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Heavy Count
|
50
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Rot Bonds
|
17
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker