General Information of This Linker
Linker ID
LIN0LVEHI
Name
US20240325556A1 Saxituzumab-chemical compound21 ADC Linker
Linker Type
Unclear
Antibody-Linker Relation
Unclear
Structure
Formula
C108H174N14O43
Isosmiles
CC([C@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)CCCCNC(CCN1C2=CC=C(NC(CCC(NCCCC[C@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(N[C@H](C(N[C@@H](C)C(NC3=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](O4)C(O)=O)C=C(C=C3)CO)=O)=O)C(C)C)=O)=O)=O)C=C2C=C1CN(NC)C)=O)=O)C(N[C@@H](C)C(NC5=C(O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@H](O6)C(O)=O)C=C(C=C5)CO)=O)=O)C
InChI
InChI=1S/C108H174N14O43/c1-68(2)89(103(140)112-70(5)99(136)117-77-20-17-72(66-123)61-82(77)162-107-95(134)91(130)93(132)97(164-107)105(142)143)119-101(138)79(115-87(128)26-31-148-37-39-152-45-47-156-53-55-160-59-57-158-51-49-154-43-41-150-35-33-146-9)15-11-13-28-110-84(125)23-24-86(127)114-75-19-22-81-74(63-75)64-76(65-121(8)109-7)122(81)30-25-85(126)111-29-14-12-16-80(116-88(129)27-32-149-38-40-153-46-48-157-54-56-161-60-58-159-52-50-155-44-42-151-36-34-147-10)102(139)120-90(69(3)4)104(141)113-71(6)100(137)118-78-21-18-73(67-124)62-83(78)163-108-96(135)92(131)94(133)98(165-108)106(144)145/h17-22,61-64,68-71,79-80,89-98,107-109,123-124,130-135H,11-16,23-60,65-67H2,1-10H3,(H,110,125)(H,111,126)(H,112,140)(H,113,141)(H,114,127)(H,115,128)(H,116,129)(H,117,136)(H,118,137)(H,119,138)(H,120,139)(H,142,143)(H,144,145)/t70-,71-,79-,80-,89-,90-,91-,92-,93-,94-,95+,96+,97-,98-,107+,108+/m0/s1
InChIKey
OIVQBJOCPMJCOP-LJDAKQHDSA-N
Pharmaceutical Properties
Molecule Weight
2356.635
Polar area
761.34
Complexity
.
xlogp Value
-2.7407
Heavy Count
165
Rot Bonds
92
Hbond acc
44
Hbond Donor
22
Each Antibody-drug Conjugate Related to This Linker