Linker Information
General Information of This Linker
| Linker ID |
LIN0LSPXT
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|---|---|---|---|---|---|---|
| Linker Name |
TW202506738A-C-027-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C21H34N4O8
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| Isosmiles |
COCCNC(CC[C@H](NC(CCCN1C(CC(C)C1=O)=O)=O)C(NCCCC(O)=O)=O)=O
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| InChI |
InChI=1S/C21H34N4O8/c1-14-13-18(28)25(21(14)32)11-4-5-17(27)24-15(7-8-16(26)22-10-12-33-2)20(31)23-9-3-6-19(29)30/h14-15H,3-13H2,1-2H3,(H,22,26)(H,23,31)(H,24,27)(H,29,30)/t14?,15-/m0/s1
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| InChIKey |
OKSVBPRCZTXLDB-LOACHALJSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
470.523
|
Polar area
|
171.21
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Complexity
|
684.8268715
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xlogp Value
|
-0.8298
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Heavy Count
|
33
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Rot Bonds
|
16
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Hbond acc
|
7
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker