Linker Information
General Information of This Linker
| Linker ID |
LIN0LRJIF
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|---|---|---|---|---|---|---|
| Linker Name |
HK40112172A+Antibody-drug conjugate (6)+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H40N6O11
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| Isosmiles |
O=C(NCCOCCOCCC(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)CCN2C(CCC2=O)=O
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| InChI |
InChI=1S/C29H40N6O11/c36-22(8-11-35-26(40)6-7-27(35)41)30-10-13-46-15-14-45-12-9-23(37)31-17-24(38)32-18-25(39)34-21(29(44)33-19-28(42)43)16-20-4-2-1-3-5-20/h1-5,21H,6-19H2,(H,30,36)(H,31,37)(H,32,38)(H,33,44)(H,34,39)(H,42,43)/t21-/m0/s1
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| InChIKey |
BTYGSQINTXPGJE-NRFANRHFSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
648.67
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Polar area
|
238.64
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Complexity
|
1151.649982
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xlogp Value
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-2.7743
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Heavy Count
|
46
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Rot Bonds
|
22
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Hbond acc
|
10
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker